Restricted valency (NPNA) n repeats and junctional epitope-based circumsporozoite protein vaccines against Plasmodium falciparum

Restricted valency (NPNA) n repeats and junctional epitope-based circumsporozoite protein vaccines against Plasmodium falciparum

Abstract The Circumsporozoite Protein (CSP) of Plasmodium falciparum contains an N-terminal region, a conserved Region I (RI), a junctional region, 25–42 copies of major (NPNA) and minor repeats followed by a C-terminal domain. The recently approved malaria vaccine, RTS,S/AS01 contains NPNAx19 and t...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Mark D. Langowski, Farhat A. Khan, Sofya Savransky, Dallas R. Brown, Arasu Balasubramaniyam, William B. Harrison, Xiaoyan Zou, Zoltan Beck, Gary R. Matyas, Jason A. Regules, Robin Miller, Lorraine A. Soisson, Adrian H. Batchelor, Sheetij Dutta
פורמט: Article
שפה:English
יצא לאור: Nature Portfolio 2022-01-01
סדרה:npj Vaccines
גישה מקוונת:https://doi.org/10.1038/s41541-022-00430-y

אינטרנט

https://doi.org/10.1038/s41541-022-00430-y

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