Constructing the boundary between potent and ineffective siRNAs by MG-algorithm with C-features

Abstract Background In siRNA based antiviral therapeutics, selection of potent siRNAs is an indispensable step, but these commonly used features are unable to construct the boundary between potent and ineffective siRNAs. Results Here, we select potent siRNAs by removing ineffective ones, where these...

Full description

Bibliographic Details
Main Authors: Xingang Jia, Qiuhong Han, Zuhong Lu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04867-9