Conserved genomic neighborhood is a strong but no perfect indicator for a direct interaction of microbial gene products

Abstract Background The order of genes in bacterial genomes is not random; for example, the products of genes belonging to an operon work together in the same pathway. The cotranslational assembly of protein complexes is deemed to conserve genomic neighborhoods even stronger than a common function....

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Bibliographic Details
Main Authors: Robert Esch, Rainer Merkl
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3200-z