Garcinol Promotes the Formation of Slow-Twitch Muscle Fibers by Inhibiting p300-Dependent Acetylation of PGC-1α

Garcinol Promotes the Formation of Slow-Twitch Muscle Fibers by Inhibiting p300-Dependent Acetylation of PGC-1α

The conversion of skeletal muscle fiber from fast-twitch to slow-twitch is crucial for sustained contractile and stretchable events, energy homeostasis, and anti-fatigue ability. The purpose of our study was to explore the mechanism and effects of garcinol on the regulation of skeletal muscle fiber...

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Bibliographic Details
Main Authors: Weilei Yao, Baoyin Guo, Taimin Jin, Zhengxi Bao, Tongxin Wang, Shu Wen, Feiruo Huang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
skeletal muscle
fiber type
garcinol
p300
PGC-1α
Online Access:https://www.mdpi.com/1422-0067/24/3/2702

Internet

https://www.mdpi.com/1422-0067/24/3/2702

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