Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights.

A novel acylpeptide hydrolase, named APEH-3(Ss), was isolated from the hypertermophilic archaeon Sulfolobus solfataricus. APEH is a member of the prolyl oligopeptidase family which catalyzes the removal of acetylated amino acid residues from the N terminus of oligopeptides. The purified enzyme shows...

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Bibliographic Details
Main Authors: Marta Gogliettino, Marco Balestrieri, Ennio Cocca, Sabrina Mucerino, Mose Rossi, Mauro Petrillo, Emanuela Mazzella, Gianna Palmieri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360023?pdf=render