Involvement of transcribed lncRNA uc.291 in hyperproliferative skin disorders

Involvement of transcribed lncRNA uc.291 in hyperproliferative skin disorders

Abstract The uc.291 transcript controls keratinocytes differentiation by physical interaction with ACTL6A and subsequent induction of transcription of the genes belonging to the epidermal differentiation complex (EDC). Uc.291 is also implicated in the dedifferentiation phenotype seen in poorly diffe...

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Bibliographic Details
Main Authors: Mara Mancini, Simone Sergio, Angela Cappello, Timea Farkas, Francesca Bernassola, Claudia Scarponi, Cristina Albanesi, Gerry Melino, Eleonora Candi
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Biology Direct
Subjects:
Epidermis
Psoriasis
Hyperproliferative skin disorders
De-differentiation
lncRNA
ACTL6A
Online Access:https://doi.org/10.1186/s13062-023-00435-0

Internet

https://doi.org/10.1186/s13062-023-00435-0

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