A new pharmacokinetic model of urinary methotrexate to assess adherence in rheumatoid arthritis

A new pharmacokinetic model of urinary methotrexate to assess adherence in rheumatoid arthritis

Background and objectives: Methotrexate (MTX) is the first-line therapy for rheumatoid arthritis (RA). While therapeutic adherence is essential to successful management, no objective MTX assay is currently available. Using population pharmacokinetic modelling (PopPK), our objective was to describe t...

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Bibliographic Details
Main Authors: Marion Geoffroy, Claire Gozalo, Céline Konecki, Loic Pauvele, Ambre Hittinger, Noemie Theate, Catherine Feliu, Jean Hugues Salmon, Zoubir Djerada
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Methotrexate
Adherence
PopPk
Rheumatoid arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222301418X

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http://www.sciencedirect.com/science/article/pii/S075333222301418X

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