Applying green analytical chemistry (GAC) for development of stability indicating HPLC method for determining clonazepam and its related substances in pharmaceutical formulations and calculating uncertainty

Clonazepam contains one benzodiazepine ring in its chemical structure which makes it vulnerable to degradation. In this study, green analytical chemistry approach was applied in attempts for the development of validated stability indicating RP-HPLC method for determining clonazepam and its related s...

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Bibliographic Details
Main Authors: Ahmed Badr Eldin, Abdallah Shalaby, Mahmoud Samy Abdallah, Moataz Ahmed Shaldam, Mohamed Adel Abdallah
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535214002925