A systematic evaluation of deep learning methods for the prediction of drug synergy in cancer.

One of the main obstacles to the successful treatment of cancer is the phenomenon of drug resistance. A common strategy to overcome resistance is the use of combination therapies. However, the space of possibilities is huge and efficient search strategies are required. Machine Learning (ML) can be a...

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Bibliographic Details
Main Authors: Delora Baptista, Pedro G Ferreira, Miguel Rocha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010200