Lipopolysaccharide-induced chronic inflammation increases female serum gonadotropins and shifts the pituitary transcriptomic landscape

Lipopolysaccharide-induced chronic inflammation increases female serum gonadotropins and shifts the pituitary transcriptomic landscape

IntroductionFemale reproductive function depends on a choreographed sequence of hormonal secretion and action, where specific stresses such as inflammation exert profound disruptions. Specifically, acute LPS-induced inflammation inhibits gonadotropin production and secretion from the pituitary, ther...

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Bibliographic Details
Main Authors: Christopher Garcia, Leandro M. Velez, Naveena Ujagar, Zena Del Mundo, Thu Nguyen, Chelsea Fox, Adam Mark, Kathleen M. Fisch, Mark A. Lawson, Antoni J. Duleba, Marcus M. Seldin, Dequina A. Nicholas
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
pituitary
FSH & LH
lipopolysaccharide (LPS)
inflammation
estrous
secretion
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1279878/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1279878/full

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