Effects of ARID1A loss on transcriptional regulation in hepatocellular carcinoma cell line PLC/PRF/5
Objective To explore the transcriptional alterations regulated by ARID1A in hepatocellular carcinoma cell line PLC/PRF/5. Methods CRISPR/Cas9 technology was utilized to generate ARID1A knockout cells. RNA-seq was then performed in both ARID1A intact and ARID1A null PLC/PRF/5 cells to generate gene e...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2020-04-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a191316.pdf |