IQGAP scaffold proteins are the multifunctional regulators of cellular signaling and malignant transformation

IQGAP scaffold proteins are the multifunctional regulators of cellular signaling and malignant transformation

Scaffold proteins coordinate the assembling of multicomponent protein complexes and participate in transduction of cellular signals via multiple signaling pathways therefore acting as important regulators of cell properties. IQ Motif Containing GTPase Activating Proteins (IQGAPs) are promising targe...

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Bibliographic Details
Main Authors: P. A. Skovorodnikova, M. S. Chesnokov, A. A. Budko, I. F. Kustova, N. L. Lazarevich
Format: Article
Language:Russian
Published: ABV-press 2017-07-01
Series:Успехи молекулярной онкологии
Subjects:
скаффолд-белки
iqgap
мультибелковый комплекс
map-киназный каскад
сигнальный путь wnt
β-катенин
опухолевая прогрессия
протоонкоген
опухолевый супрессор
Online Access:https://umo.abvpress.ru/jour/article/view/93

Internet

https://umo.abvpress.ru/jour/article/view/93

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