Pyroptosis: A Common Feature of Immune Cells of Haemodialysis Patients

Pyroptosis: A Common Feature of Immune Cells of Haemodialysis Patients

NLRP-3 inflammasome activation can result in interleukin-1β (IL-1β) release and inflammatory cell death (pyroptosis). Caspase-1 is able to trigger both processes. However, other caspases, caspase-4, -5 and -8, are believed to initiate pyroptosis without affecting IL-1 secretion. In this study, we ev...

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Bibliographic Details
Main Authors: Christof Ulrich, Leonie Kneser, Roman Fiedler, Julia Beckert, Susann Wildgrube, Eric Seibert, Sylvia Fick, Christoph Schäfer, Silke Markau, Bogusz Trojanowicz, Matthias Girndt
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Toxins
Subjects:
haemodialysis
hypertension
pyroptosis
indoxyl sulfate
caspase-1
caspase-4
Online Access:https://www.mdpi.com/2072-6651/13/12/839

Internet

https://www.mdpi.com/2072-6651/13/12/839

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