Parallel selection on TRPV6 in human populations.

We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel soft sweep events in humans. A novel modification of the extended haplotype homozygosity (EHH) test wa...

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Bibliographic Details
Main Authors: David A Hughes, Kun Tang, Rainer Strotmann, Torsten Schöneberg, Jean Prenen, Bernd Nilius, Mark Stoneking
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18301763/pdf/?tool=EBI