Azelnidipine Exhibits In Vitro and In Vivo Antiviral Effects against Flavivirus Infections by Targeting the Viral RdRp

Azelnidipine Exhibits In Vitro and In Vivo Antiviral Effects against Flavivirus Infections by Targeting the Viral RdRp

Flaviviruses, represented by Zika and dengue virus (ZIKV and DENV), are widely present around the world and cause various diseases with serious consequences. However, no antiviral drugs have been clinically approved for use against them. Azelnidipine (ALP) is a dihydropyridine calcium channel blocke...

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Bibliographic Details
Main Authors: Zhuang Wang, Yunzheng Yan, Qingsong Dai, Yijie Xu, Jiye Yin, Wei Li, Yuexiang Li, Xiaotong Yang, Xiaojia Guo, Miaomiao Liu, Xingjuan Chen, Ruiyuan Cao, Wu Zhong
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
azelnidipine
Zika virus
antiviral
flavivirus
RdRp
Online Access:https://www.mdpi.com/1999-4915/14/6/1228

Internet

https://www.mdpi.com/1999-4915/14/6/1228

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