Novel ratio-metric features enable the identification of new driver genes across cancer types

Abstract An emergent area of cancer genomics is the identification of driver genes. Driver genes confer a selective growth advantage to the cell. While several driver genes have been discovered, many remain undiscovered, especially those mutated at a low frequency across samples. This study defines...

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Bibliographic Details
Main Authors: Malvika Sudhakar, Raghunathan Rengaswamy, Karthik Raman
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04015-y