FUNDC1-induced mitophagy protects spinal cord neurons against ischemic injury

Abstract Local ischemia and hypoxia are the most important pathological processes in the early phase of secondary spinal cord injury (SCI), in which mitochondria are the main target of ischemic injury. Mitochondrial autophagy, also known as mitophagy, acts as a selective autophagy that specifically...

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Bibliographic Details
Main Authors: Dehui Chen, Linquan Zhou, Gang Chen, Taotao Lin, Jiemin Lin, Xin Zhao, Wenwen Li, Shengyu Guo, Rongcan Wu, Zhenyu Wang, Wenge Liu
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01780-9