Mitochondrial and Cellular Function in Fibroblasts, Induced Neurons, and Astrocytes Derived from Case Study Patients: Insights into Major Depression as a Mitochondria-Associated Disease

Mitochondrial and Cellular Function in Fibroblasts, Induced Neurons, and Astrocytes Derived from Case Study Patients: Insights into Major Depression as a Mitochondria-Associated Disease

The link between mitochondria and major depressive disorder (MDD) is increasingly evident, underscored both by mitochondria’s involvement in many mechanisms identified in depression and the high prevalence of MDD in individuals with mitochondrial disorders. Mitochondrial functions and energy metabol...

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Bibliographic Details
Main Authors: Iseline Cardon, Sonja Grobecker, Selin Kücükoktay, Stefanie Bader, Tatjana Jahner, Caroline Nothdurfter, Kevin Koschitzki, Mark Berneburg, Bernhard H. F. Weber, Heidi Stöhr, Marcus Höring, Gerhard Liebisch, Frank Braun, Tanja Rothammer-Hampl, Markus J. Riemenschneider, Rainer Rupprecht, Vladimir M. Milenkovic, Christian H. Wetzel
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
major depressive disorder
mitochondrial functions
mitochondriopathy
treatment-resistant depression
iPS-neurons
iPS-astrocytes
Online Access:https://www.mdpi.com/1422-0067/25/2/963

Internet

https://www.mdpi.com/1422-0067/25/2/963

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