Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

Abstract Background Subtle adjustment of the activation status of CNS resident microglia and peripheral macrophages, to promote their neuroprotective and neuroregenerative functions, may facilitate research towards curing neurodegenerative disorders. In the present study, we investigated whether tar...

Descrizione completa

Dettagli Bibliografici
Autori principali: Somayyeh Hamzei Taj, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Alessandra Quarta, Jelle Praet, Annemie Van der Linden, Peter Ponsaerts, Mathias Hoehn
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2018-06-01
Serie:Journal of Neuroinflammation
Soggetti:
Stroke
Microglia/macrophage polarization
Interleukin 13
Mesenchymal stem cells
Neuroinflammation
Accesso online:http://link.springer.com/article/10.1186/s12974-018-1212-7

Accesso online

http://link.springer.com/article/10.1186/s12974-018-1212-7

Documenti analoghi