Ahf-Caltide, a Novel Polypeptide Derived from Calpastatin, Protects against Oxidative Stress Injury by Stabilizing the Expression of Ca<sub>V</sub>1.2 Calcium Channel

Ahf-Caltide, a Novel Polypeptide Derived from Calpastatin, Protects against Oxidative Stress Injury by Stabilizing the Expression of Ca<sub>V</sub>1.2 Calcium Channel

Reperfusion after ischemia would cause massive myocardial injury, which leads to oxidative stress (OS). Calcium homeostasis imbalance plays an essential role in myocardial OS injury. Ca<sub>V</sub>1.2 calcium channel mediates calcium influx into cardiomyocytes, and its activity is modula...

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Bibliographic Details
Main Authors: Yingchun Xue, Shi Zhou, Ling Yan, Yuelin Li, Xingrong Xu, Xianghui Wang, Etsuko Minobe, Masaki Kameyama, Liying Hao, Huiyuan Hu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Ahf-caltide
myocardial oxidative stress injury
Ca<sub>V</sub>1.2 calcium channel
calpastatin domain L
Online Access:https://www.mdpi.com/1422-0067/24/21/15729

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https://www.mdpi.com/1422-0067/24/21/15729

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