Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach

Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach

Before entering the cell, the SARS-CoV-2 spike glycoprotein receptor-binding domain (RBD) binds to the human angiotensin-converting enzyme 2 (hACE2) receptor. Hence, this RBD is a critical target for the development of antiviral agents. Recent studies have discovered that SARS-CoV-2 variants with mu...

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Bibliographic Details
Main Authors: Trina Ekawati Tallei, Fatimawali, Ahmad Akroman Adam, Mona M. Elseehy, Ahmed M. El-Shehawi, Eman A. Mahmoud, Adinda Dwi Tania, Nurdjannah Jane Niode, Diah Kusumawaty, Souvia Rahimah, Yunus Effendi, Rinaldi Idroes, Ismail Celik, Md. Jamal Hossain, Talha Bin Emran
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
bromelain
peptide
SARS-CoV-2 variants
in silico
receptor-binding domain
RBD mutation
Online Access:https://www.mdpi.com/1420-3049/27/1/260

Internet

https://www.mdpi.com/1420-3049/27/1/260

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