Physiological and pharmacological characterization of transmembrane acid extruders in cultured human umbilical artery smooth muscle cells

Physiological and pharmacological characterization of transmembrane acid extruders in cultured human umbilical artery smooth muscle cells

Background: Intracellular pH (pH i) is a pivotal factor for cellular functions and homeostasis. Apart from passive intracellular buffering capacity, active transmembrane transporters responsible for kinetic changes of pH i impacts. Acid extrusion transporters such as Na + /H + exchanger (NHE) and Na...

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Bibliographic Details
Main Authors: Gunng-Shinng Chen, Ching-Hsia Wu, Chi-Chiuan Liau, Chih-Chin Hsu, Jah-Yao Liu, Gwo-Jang Wu, Chi-Chung Chou, Shih-Hurng Loh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Medical Sciences
Subjects:
Human umbilical artery smooth muscle cells
intracellular pH
Na + -H + exchanger
Na +-HCO3- cotransporter
fluorescence dye-2′
7′-bis(2-carboxethyl)-5(6)-carboxy-fluorescein-acetoxymethyl
Online Access:http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=5;spage=208;epage=217;aulast=Chen

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http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=5;spage=208;epage=217;aulast=Chen

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