Bone Marrow Mesenchymal Stem Cells Overexpressing HIF-1α Prevented the Progression of Glucocorticoid-Induced Avascular Osteonecrosis of Femoral Heads in Mice

Bone Marrow Mesenchymal Stem Cells Overexpressing HIF-1α Prevented the Progression of Glucocorticoid-Induced Avascular Osteonecrosis of Femoral Heads in Mice

Glucocorticoid (GC)-induced avascular osteonecrosis of femoral head (AOFH) is a devastating complication, and no cures are currently available for it. Previous studies have demonstrated that implantation of bone marrow mesenchymal stem cells (BMMSCs) may prevent the progression of pre-collapse AOFH....

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Bibliographic Details
Main Authors: Xin-Xin Zhang, Xu Liang, Sen-Rui Li, Kuang-Jin Guo, Dai-Feng Li, Tian-Fang Li
Format: Article
Language:English
Published: SAGE Publishing 2022-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897221082687

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https://doi.org/10.1177/09636897221082687

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