Determination of Tedizolid in Bacterial Growth Medium Mueller-Hinton Broth by High-Performance Liquid Chromatography and Its Application to an In Vitro Study in the Hollow-Fiber Infection Model

Pharmacokinetic/pharmacodynamic (PKPD) studies of anti-infectives are frequently performed in in vitro infection models where accurate quantification of antibiotic concentrations in bacterial growth media is crucial to establish PK/PD relationships. Here, a sensitive and rapid high-performance liqui...

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Bibliographic Details
Main Authors: Khalid Iqbal, Aliki Milioudi, Elena Haro Martínez, Sebastian Georg Wicha
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/8/9/141