Short‐term outcomes of a prospective multicenter phase II trial of total neoadjuvant therapy for locally advanced rectal cancer in Japan (ENSEMBLE‐1)

Short‐term outcomes of a prospective multicenter phase II trial of total neoadjuvant therapy for locally advanced rectal cancer in Japan (ENSEMBLE‐1)

Abstract Aim To evaluate the feasibility and safety of total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer (LARC) in Japan. Methods This prospective, multicenter, open‐label, single‐arm phase II trial was conducted at five institutions. The key eligibility criteria were a...

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Bibliographic Details
Main Authors: Yoshinori Kagawa, Jun Watanabe, Mamoru Uemura, Koji Ando, Akira Inoue, Koji Oba, Ichiro Takemasa, Eiji Oki
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Annals of Gastroenterological Surgery
Subjects:
locally advanced rectal cancer
neoadjuvant chemotherapy
non‐operative management
pathological complete response
radiation therapy
total mesorectal excision
Online Access:https://doi.org/10.1002/ags3.12715

Internet

https://doi.org/10.1002/ags3.12715

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