Domestic Pig Unlikely Reservoir for MERS-CoV

Domestic Pig Unlikely Reservoir for MERS-CoV

We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikel...

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Bibliographic Details
Main Authors: Emmie de Wit, Friederike Feldmann, Eva Horne, Cynthia Martellaro, Elaine Haddock, Trenton Bushmaker, Kyle Rosenke, Atsushi Okumura, Rebecca Rosenke, Greg Saturday, Dana Scott, Heinz Feldmann
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-06-01
Series:Emerging Infectious Diseases
Subjects:
Middle East respiratory syndrome coronavirus
MERS-CoV
animal models
domestic pig
dipeptidyl peptidase 4
DPP4
Online Access:https://wwwnc.cdc.gov/eid/article/23/6/17-0096_article

Internet

https://wwwnc.cdc.gov/eid/article/23/6/17-0096_article

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