Inhibition of TRIF-Dependent Inflammation Decelerates Afterload-Induced Myocardial Remodeling

Inhibition of TRIF-Dependent Inflammation Decelerates Afterload-Induced Myocardial Remodeling

Pressure-overload-induced cardiac hypertrophy represents one cause of the development of heart failure. The aim of this study is to characterize the influence of the TIR-domain-containing adapter-inducing interferon-β (TRIF) during afterload-induced myocardial remodeling. After trans-aortic constric...

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Bibliographic Details
Main Authors: Stephanie I. Bettink, Jan-Christian Reil, Andrey Kazakov, Christina Körbel, Dominic Millenaar, Ulrich Laufs, Bruno Scheller, Michael Böhm, Stephan H. Schirmer
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
TRIF
fibrosis
hypertrophy
inflammation
afterload
Online Access:https://www.mdpi.com/2227-9059/10/10/2636

Internet

https://www.mdpi.com/2227-9059/10/10/2636

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