Spironolactone inhibits the activity of the Na/H exchanger in the aorta of mineralocorticoid-induced hypertensive rats

Spironolactone inhibits the activity of the Na/H exchanger in the aorta of mineralocorticoid-induced hypertensive rats

Introduction: Aldosterone can induce changes in the expression or activity of Na + /H + exchanger isoform 1 (NHE–1) in vascular smooth muscle cells. We aimed to clarify whether chronic mineralocorticoid receptor activation exerts an effect on the activity of NHE–1 in the aorta of mineralocorticoid-i...

Full description

Bibliographic Details
Main Authors: Juan E Carreño, Fernando J Verdugo, Felipe Contreras, Felipe A Montellano, Sebastian Veloso, Kurt A Schalper, Mauricio Sandoval, Sandra Villanueva, Elisa Marusic, Carlos E Irarrazabal
Format: Article
Language:English
Published: SAGE Publications 2015-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320315587193

Internet

https://doi.org/10.1177/1470320315587193

Similar Items