Sequencing and characterization of an L-asparaginase gene from a new species of Penicillium section Citrina isolated from Cerrado

Abstract The enzyme L-asparaginase (L-ASNase) is used in the treatment of Acute Lymphoblastic Leukemia. The preparations of this enzyme for clinical use are derived from bacterial sources and its use is associated with serious adverse reactions. In this context, it is important to find new sources o...

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Bibliographic Details
Main Authors: Kellen C. R. Andrade, Rildo A. Fernandes, Danilo Batista Pinho, Marcela M. de Freitas, Edivaldo Ximenes Ferreira Filho, Adalberto Pessoa, João Inácio Silva, Perola O. Magalhães
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97316-1