Cellular and Molecular Mechanisms of the Tumor Stroma in Colorectal Cancer: Insights into Disease Progression and Therapeutic Targets

Cellular and Molecular Mechanisms of the Tumor Stroma in Colorectal Cancer: Insights into Disease Progression and Therapeutic Targets

Colorectal cancer (CRC) is a major health burden worldwide and is the third most common type of cancer. The early detection and diagnosis of CRC is critical to improve patient outcomes. This review explores the intricate interplay between the tumor microenvironment, stromal interactions, and the pro...

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Bibliographic Details
Main Authors: Nikolay Shakhpazyan, Liudmila Mikhaleva, Arkady Bedzhanyan, Zarina Gioeva, Nikolay Sadykhov, Alexander Mikhalev, Dmitri Atiakshin, Igor Buchwalow, Markus Tiemann, Alexander Orekhov
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
colorectal cancer
conserved oncogenic signatures
gut-associated lymphoid tissue
gut microbiome
metastasis
tumor budding
Online Access:https://www.mdpi.com/2227-9059/11/9/2361

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https://www.mdpi.com/2227-9059/11/9/2361

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