Cooperativity in Proteasome Core Particle Maturation

Summary: Proteasomes are multi-subunit protease complexes found in all domains of life. The maturation of the core particle (CP), which harbors the active sites, involves dimerization of two half CPs (HPs) and an autocatalytic cleavage that removes β propeptides. How these steps are regulated remain...

Full description

Bibliographic Details
Main Authors: Anjana Suppahia, Pushpa Itagi, Alicia Burris, Faith Mi Ge Kim, Alexander Vontz, Anupama Kante, Seonghoon Kim, Wonpil Im, Eric J. Deeds, Jeroen Roelofs
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302753