Modulation of Methotrexate Release from Nano-Hydrogels via Drug-Transition Metal Complexation
Despite the extensive application of methotrexate (MTX) as a chemotherapeutic agent and an immune system suppressor, its therapeutic implementation has been limited due to its poor pharmacokinetics, saturable cellular transport, and insufficient response in some conditions. These limitations have re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Shiraz University of Medical Sciences
2020-09-01
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| Series: | Trends in Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://tips.sums.ac.ir/article_46833_5a48e389ff2e35d1ca9d30dd7e4b48bf.pdf |