Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II

Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II

Background Prolonged activation of angiotensin II is the main mediator that contributes to the development of heart diseases, so converting angiotensin II into angiotensin 1‐7 has emerged as a new strategy to attenuate detrimental effects of angiotensin II. Prolylcarboxypeptidase is a lysosomal pro‐...

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Bibliographic Details
Main Authors: Binh Y. Nguyen, Fangchao Zhou, Pablo Binder, Wei Liu, Susanne S. Hille, Xiaojing Luo, Min Zi, Hongyuan Zhang, Antony Adamson, Fozia Z. Ahmed, Sam Butterworth, Elizabeth J. Cartwright, Oliver J. Müller, Kaomei Guan, Elizabeth M. Fitzgerald, Xin Wang
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
hypertension
hypertrophy
lysosome
prolylcarboxylpeptidase
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.028298

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.122.028298

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