A systematic study of HIF1A cofactors in hypoxic cancer cells

Abstract Hypoxia inducible factor 1 alpha (HIF1A) is a transcription factor (TF) that forms highly structural and functional protein–protein interactions with other TFs to promote gene expression in hypoxic cancer cells. However, despite the importance of these TF-TF interactions, we still lack a co...

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Bibliographic Details
Main Authors: Yuxiang Zhang, Saidi Wang, Haiyan Hu, Xiaoman Li
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23060-9