miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 signaling and blocking neuro-cartilage interaction

miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 signaling and blocking neuro-cartilage interaction

Osteoarthritis (OA) is a painful degenerative joint disease and is the leading cause of chronic disability among elderly individuals. To improve the quality of life for patients with OA, the primary goal for OA treatment is to relieve the pain. During OA progression, nerve ingrowth was observed in s...

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Bibliographic Details
Main Authors: Ke Lu, Qingyun Wang, Liuzhi Hao, Guizheng Wei, Tingyu Wang, William W. Lu, Guozhi Xiao, Liping Tong, Xiaoli Zhao, Di Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-08-01
Series:Bioactive Materials
Subjects:
miR-204
LRP1
Neuro-cartilage interaction
Osteoarthritis
Pain
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23000877

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X23000877

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