High Levels of Circulating Monocytic Myeloid-Derived Suppressive-Like Cells Are Associated With the Primary Resistance to Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer: An Exploratory Analysis

High Levels of Circulating Monocytic Myeloid-Derived Suppressive-Like Cells Are Associated With the Primary Resistance to Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer: An Exploratory Analysis

BackgroundImmunotherapy has become the standard of care for non-small cell lung cancer (NSCLC) patients. Some patients experience primary resistance to immunotherapy. Currently, we lack a marker of resistance to immunotherapy. Myeloid-derived suppressive-like cells (MDSCs) can reduce tumor response...

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Bibliographic Details
Main Authors: Giuseppe Bronte, Elisabetta Petracci, Serena De Matteis, Matteo Canale, Ilaria Zampiva, Ilaria Priano, Paola Cravero, Kalliopi Andrikou, Marco Angelo Burgio, Paola Ulivi, Angelo Delmonte, Lucio Crinò
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
myeloid-derived suppressive cells
primary resistance
immunotherapy
non-small cell lung cancer
immune checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.866561/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.866561/full

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