Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic agents for hepatocellular carcinoma

Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic agents for hepatocellular carcinoma

BackgroundThe development of HCC is often associated with extensive metabolic disturbances. Single cell RNA sequencing (scRNA-seq) provides a better understanding of cellular behavior in the context of complex tumor microenvironments by analyzing individual cell populations. MethodsThe Cancer Genome...

Full description

Bibliographic Details
Main Authors: Cuifang Han, Jiaru Chen, Jing Huang, Riting Zhu, Jincheng Zeng, Hongbing Yu, Zhiwei He
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
cancer metabolism
hepatocellular carcinoma
malignant hepatocytes
prognostic biomarker
single-cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1104262/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1104262/full

Similar Items