Deciphering the structure, growth and assembly of amyloid-like fibrils using high-speed atomic force microscopy.

Formation of fibrillar structures of proteins that deposit into aggregates has been suggested to play a key role in various neurodegenerative diseases. However mechanisms and dynamics of fibrillization remains to be elucidated. We have previously established that lithostathine, a protein overexpress...

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Bibliographic Details
Main Authors: Pierre-Emmanuel Milhiet, Daisuke Yamamoto, Olivia Berthoumieu, Patrice Dosset, Christian Le Grimellec, Jean-Michel Verdier, Stéphane Marchal, Toshio Ando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2951901?pdf=render