Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response

Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response

Abstract The pathogenesis of diabetic kidney disease (DKD) is complicated. Current clinical treatments fail to achieve satisfactory efficacy in the prevention of DKD progression, it urgently needs novel and effective treatment for DKD. In this study, we firstly demonstrated that renal lipid metaboli...

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Bibliographic Details
Main Authors: Zhonglian Cao, Hui Zhao, Jiajun Fan, Yilan Shen, Lei Han, Guangjun Jing, Xian Zeng, Xin Jin, Zeguo Zhu, Qi Bian, Yanyang Nan, Xiaozhi Hu, Xiaobin Mei, Dianwen Ju, Ping Yang
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01304-5

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https://doi.org/10.1038/s41420-023-01304-5

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