miR‐133b as a potential regulator of a synaptic NPTX2 protein in Alzheimer's disease

Abstract A synaptic protein, Neuronal Pentraxin 2 (NPTX2), has emerged as a pivotal biomarker for Alzheimer's dementia (AD). We identified candidate miRNAs targeting NPTX2 and performed association and mediation analyses using multi‐omics data (N = 702). Among 44 candidate miRNAs, miR‐133b was...

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Bibliographic Details
Main Authors: Sang‐Won Han, Young Ho Park, Paula J Bice, David A. Bennett, SangYun Kim, Andrew J. Saykin, Kwangsik Nho
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52175