SELENOF Controls Proliferation and Cell Death in Breast-Derived Immortalized and Cancer Cells

SELENOF Controls Proliferation and Cell Death in Breast-Derived Immortalized and Cancer Cells

SELENOF expression is significantly lower in aggressive breast tumors compared to normal tissue, indicating that its reduction or loss may drive breast tumorigenesis. Deletion of SELENOF in non-tumorigenic immortalized breast epithelial MCF-10A cells resulted in enhanced proliferation, both in adher...

Full description

Bibliographic Details
Main Authors: Roudy C. Ekyalongo, Brenna Flowers, Tanu Sharma, Alexandra Zigrossi, An Zhang, Anaisa Quintanilla-Arteaga, Kanishka Singh, Irida Kastrati
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
breast cancer
selenoprotein F (SELENOF)
tumor suppressor
acinar growth
proliferation
cell death
Online Access:https://www.mdpi.com/2072-6694/15/14/3671

Internet

https://www.mdpi.com/2072-6694/15/14/3671

Similar Items