Indole-Based and Cyclopentenylindole-Based Analogues Containing Fluorine Group as Potential <sup>18</sup>F-Labeled Positron Emission Tomography (PET) G-Protein Coupled Receptor 44 (GPR44) Tracers

Indole-Based and Cyclopentenylindole-Based Analogues Containing Fluorine Group as Potential <sup>18</sup>F-Labeled Positron Emission Tomography (PET) G-Protein Coupled Receptor 44 (GPR44) Tracers

Recently, growing evidence of the relationship between G-protein coupled receptor 44 (GPR44) and the inflammation-cancer system has garnered tremendous interest, while the exact role of GPR44 has not been fully elucidated. Currently, there is a strong and urgent need for the development of non-invas...

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Bibliographic Details
Main Authors: Runkai Yin, Kelly X. Huang, Lina A. Huang, Melinda Ji, Hanyi Zhao, Kathy Li, Anna Gao, Jiaqi Chen, Zhixuan Li, Tianxiong Liu, John E. Shively, Fouad Kandeel, Junfeng Li
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
G-protein coupled receptor 44 (GPR44)
cancer-related inflammation
inflammation-induced cancer
positron emission tomography (PET) imaging
fluorine-18
indole-based analogues
Online Access:https://www.mdpi.com/1424-8247/16/9/1203

Internet

https://www.mdpi.com/1424-8247/16/9/1203

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