Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides

The nonenzymatic replication of RNA is a potential transitional stage between the prebiotic chemistry of nucleotide synthesis and the canonical RNA world in which RNA enzymes (ribozymes) catalyze replication of the RNA genomes of primordial cells. However, the plausibility of nonenzymatic RNA replic...

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Bibliographic Details
Main Authors: Noam Prywes, J Craig Blain, Francesca Del Frate, Jack W Szostak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/17756