Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage

Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage

Circulating extracellular vesicles (EVs) are proposed to participate in enhancing pathways of recovery after stroke through paracrine signaling. To verify this hypothesis in a proof-of-concept study, blood-derived allogenic EVs from rats and xenogenic EVs from humans who experienced spontaneous good...

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Bibliographic Details
Main Authors: Fernando Laso-García, Laura Casado-Fernández, Dolores Piniella, Mari Carmen Gómez-de Frutos, Jone Karmele Arizaga-Echebarria, María Pérez-Mato, Elisa Alonso-López, Laura Otero-Ortega, Susana Belén Bravo, María del Pilar Chantada-Vázquez, José Avendaño-Ortiz, Eduardo López-Collazo, María Isabel Lumbreras-Herrera, Angelo Gámez-Pozo, Blanca Fuentes, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, María Alonso de Leciñana
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Special Issue - Exploiting Extracellular Vesicles as Therapeutic Agents
extracellular vesicles
intracerebral hemorrhage
preclinical studies
proteomics
safety
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123000653

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http://www.sciencedirect.com/science/article/pii/S2162253123000653

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