Effects of intramuscularly injected plant-derived antimicrobials in the mouse model

Abstract With increasing antibiotic resistance, the use of plant derived antimicrobials (PDAs) has gained momentum. Here, we investigated the toxicity of trans-cinnamaldehyde, eugenol, and carvacrol after intramuscular injection in mice. Two doses of each PDA—300 and 500 mg/kg body weight—and vehicl...

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Bibliographic Details
Main Authors: Elizabeth J. Johnson, Jingyue Ellie Duan, Kanokwan Srirattana, Kumar Venkitanarayanan, Edan R. Tulman, Xiuchun Cindy Tian
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09705-9