Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-<i>O</i>-Benzyl Estrone Analogs

Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-<i>O</i>-Benzyl Estrone Analogs

Four diastereomers of 16-azidomethyl substituted 3-<i>O</i>-benzyl estradiol (<b>1</b>–<b>4</b>) and their two estrone analogs (<b>16AABE</b> and <b>16BABE</b>) were tested for their antiproliferative properties against human gynecological...

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Bibliographic Details
Main Authors: Seyyed Ashkan Senobar Tahaei, Ágnes Kulmány, Renáta Minorics, Anita Kiss, Zoltán Szabó, Péter Germán, Gábor J. Szebeni, Nikolett Gémes, Erzsébet Mernyák, István Zupkó
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
estrone analogs
antiproliferative effect
metastasis
apoptosis
tubulin polymerization
breast cancer
Online Access:https://www.mdpi.com/1422-0067/24/18/13749

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https://www.mdpi.com/1422-0067/24/18/13749

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