Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice.

Scrub typhus is a poorly studied but life-threatening disease caused by the intracellular bacterium Orientia tsutsugamushi (Ot). Cellular and humoral immunity in Ot-infected patients is not long-lasting, waning as early as one-year post-infection; however, its underlying mechanisms remain unclear. T...

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Bibliographic Details
Main Authors: Casey Gonzales, Yuejin Liang, James Fisher, Galen Card, Jiaren Sun, Lynn Soong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011090