The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies

Abstract Background The α2 agonists, dexmedetomidine and clonidine, are used as sedative drugs during critical illness. These drugs may have anti-inflammatory effects, which might be relevant to critical illness, but a systematic review of published literature has not been published. We reviewed ani...

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Bibliographic Details
Main Authors: Charles A. Flanders, Alistair S. Rocke, Stuart A. Edwardson, J. Kenneth Baillie, Timothy S. Walsh
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-019-2690-4