Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences

Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences

Amylin and leptin synergistically interact in the arcuate nucleus of the hypothalamus (ARC) to control energy homeostasis. Our previous rodent studies suggested that amylin-induced interleukin-6 release from hypothalamic microglia may modulate leptin signaling in agouti-related peptide expressing ne...

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Bibliographic Details
Main Authors: Bernd Coester, Thomas A. Lutz, Christelle Le Foll
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Metabolites
Subjects:
amylin
leptin
hypothalamus
AgRP
CTR
CALCR
Online Access:https://www.mdpi.com/2218-1989/12/1/51

Internet

https://www.mdpi.com/2218-1989/12/1/51

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