Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies. Under the umbrella of the Organisation for Economic Co-operation and Developm...

Full description

Bibliographic Details
Main Authors: Katharina Koch, Kristina Bartmann, Julia Hartmann, Julia Kapr, Jördis Klose, Eliška Kuchovská, Melanie Pahl, Kevin Schlüppmann, Etta Zühr, Ellen Fritsche
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Toxicology
Subjects:
developmental neurotoxicity
neural progenitor cells
neurons
oligodendrocytes
new approach methodologies
3D in vitro models
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2022.816370/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2022.816370/full

Similar Items